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PepGen: Q4 Newsletter & Clinical Trial Now Recruiting

January 31, 2024

PepGen has released their Q4 Advocacy Newsletter, including an update for the Canadian Duchenne muscular dystrophy community regarding the CONNECT1-ED051 clinical trial:

  • Successfully dosed the first person in the CONNECT1-EDO51 study.
  • Preliminary data for the safety, exon 51 skipping and dystrophin production is expected in mid-2024 for the 5mg/kg cohort.

Read more about CONNECT1-ED051, as well as the anticipated initiation CONNECT2-EDO51 below:

PepGen is actively recruiting participants for their study to evaluate the safety and tolerability of multiple ascending intravenous (IV) doses of PGN-EDO51 administered to participants with Duchenne muscular dystrophy at the following Canadian locations:

  • Fredericton, New Brunswick – Stan Cassidy Centre for Rehabilitation
  • Ottawa, Ontario – Children’s Hospital of Eastern Ontario (CHEO)
  • Toronto, Ontario – The Hospital for Sick Children (SickKids)
  • Québec, Quebec – CHU de Québec

For information on clinical trial locations, please contact Patient Advocacy.

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